PLENHYAGE® XL Medium 1x2 ml
Product Overview
PLENHYAGE® XL Medium 1x2 ml is an advanced injectable polynucleotide-based biorevitalisation treatment developed to support skin regeneration, improve tissue quality and help restore the physiological condition of ageing, photoaged or stressed skin.
Formulated with high-molecular-weight polynucleotides at a concentration of 2.0%, PLENHYAGE® XL Medium provides a balanced polynucleotide treatment designed for professional aesthetic medicine.
Its regenerative and hydrating properties help create a favourable dermal environment for fibroblast activity, supporting improvements in skin elasticity, texture and overall quality.
Unlike conventional hyaluronic acid dermal fillers, PLENHYAGE® XL Medium is not primarily intended to create volume or alter facial contours. Its action focuses on biorevitalisation and progressive tissue regeneration, promoting a natural improvement in the appearance and quality of the skin.
Technology & Composition
PLENHYAGE® XL Medium is based on highly purified, high-molecular-weight polynucleotides (PN) obtained from DNA of natural origin.
Polynucleotides support the extracellular environment through their hydrating and regenerative properties, helping create favourable conditions for fibroblast activity, cellular turnover and the restoration of tissue elasticity.
The 2.0% concentration provides an intermediate-strength formulation within the PLENHYAGE® XL range, making it suitable for professional protocols focused on general skin biorevitalisation and progressive improvement of tissue quality.
Composition:
High-Molecular-Weight Polynucleotides (PN): 2.0%
Polynucleotide concentration: 20 mg/ml
Highly purified DNA-derived material
Biocompatible and resorbable formulation
Sterile injectable gel
Packaging
Each package contains:
1 pre-filled glass syringe of 2 ml
40 mg total polynucleotides per syringe
2 sterile disposable needles
Indications & Treatment Areas
PLENHYAGE® XL Medium is intended for professional biorevitalisation and regenerative aesthetic protocols focused on:
Loss of skin elasticity
Reduced skin firmness and tone
Dehydrated or stressed skin
Dull or tired-looking skin
Signs of skin ageing
Photoaged skin
Improvement of overall skin texture and quality
Dermal biorevitalisation
Support of physiological tissue regeneration
Selected areas of fibrotic tissue
Common treatment areas include:
Face
Neck
Décolleté
Hands
Selected body areas requiring improvement in skin elasticity and tissue quality
Clinical Benefits
Contains 2.0% high-molecular-weight polynucleotides
Supports fibroblast activity
Promotes progressive skin biorevitalisation
Supports physiological tissue regeneration
Helps improve skin elasticity and firmness
Provides hydrating action within the treated tissue
Helps improve overall skin texture and quality
Supports cellular turnover
Helps address signs associated with ageing and photoageing
Provides progressive, natural-looking skin rejuvenation
Biocompatible and resorbable formulation
Does not act as a conventional volumising dermal filler
Treatment Protocol
PLENHYAGE® XL Medium is supplied in a ready-to-use pre-filled syringe and does not require reconstitution.
Before administration, the product should be prepared and handled in accordance with the manufacturer's Instructions for Use.
Administration should be performed using appropriate professional injection techniques according to the treatment area, individual patient assessment and applicable clinical protocol.
General product information includes:
Each pre-filled syringe contains 2 ml of product.
The formulation contains 20 mg/ml of high-molecular-weight polynucleotides.
Appropriate professional microinjection techniques may be selected according to the treatment area and individual patient assessment.
Treatment may consist of a course of sessions followed by maintenance treatments according to the manufacturer's protocol and individual patient requirements.
Treatment intervals and the total number of sessions should be determined according to the patient's skin condition, treatment objectives and professional assessment.
Treatment should only be performed by appropriately qualified healthcare professionals experienced in injectable polynucleotide and skin biorevitalisation treatments.
Duration of Results
PLENHYAGE® XL Medium is designed to produce a progressive biorevitalising and regenerative response rather than immediate volumisation.
Improvements in hydration, elasticity, texture and overall skin quality develop progressively as the treated tissue responds to the polynucleotide-based treatment.
The duration and degree of improvement may vary according to patient characteristics, age, skin condition, treatment area, number of sessions and maintenance protocol.
A course of treatments followed by appropriate maintenance may be recommended according to the manufacturer's Instructions for Use and professional assessment.
Manufacturer & Regulatory Information
Manufacturer: Bioformula S.r.l.
Brand: PLENHYAGE®
Country of Origin: Italy
Product Type: Injectable High-Molecular-Weight Polynucleotide (PN) Biorevitalisation Treatment
Polynucleotide Concentration: 2.0% (20 mg/ml)
Medical Device: Class III
CE Marked – CE 0373
Biocompatible and resorbable medical device
Intended for professional medical use in accordance with the manufacturer's Instructions for Use and applicable medical device regulations.
For Professional Use Only
As a trusted distributor within the medical aesthetics sector, AesthiSave® emphasises that all products supplied are intended exclusively for professional use.
These treatments must only be performed by appropriately qualified healthcare professionals with suitable training and clinical experience, ensuring the highest standards of patient safety and care.
