MASTELLI PLINEST EYE 1x2 ml – Polynucleotide-Based Periocular Bioreparant
MASTELLI PLINEST EYE, developed by Mastelli S.r.l. Officina Bio-Farmaceutica (Italy), is an advanced polynucleotide injectable specifically formulated for the periocular region.
It targets delicate under-eye skin to improve texture, elasticity, hydration, and firmness, visibly reducing signs of fatigue and fine lines.
Product Overview
PLINEST EYE utilizes the patented PN-HPT® (Polynucleotide High Purification Technology), delivering highly purified DNA fragments that promote cellular regeneration, fibroblast activation, and dermal repair.
This treatment revitalizes the fragile eye contour by improving tissue elasticity and hydration, providing a brighter, smoother, and more youthful appearance.
Technology & Composition
Active Ingredient: Highly purified polynucleotides (PN-HPT®)
Concentration: 7.5 mg/ml
Formulation: Sterile, resorbable, viscoelastic gel for intradermal use
Mechanism of Action: Cellular bio-repair through fibroblast stimulation, collagen remodeling, and hydration enhancement
Key Features:
PN-HPT® technology ensures exceptional purity and safety
Promotes tissue elasticity and smoothness in delicate periocular skin
Deeply hydrates and rebalances the extracellular matrix
Packaging
1 pre-filled syringe of 2 ml
2 sterile 30G ½” needles
Product labels and professional instructions
Indications & Treatment Areas
MASTELLI PLINEST EYE is indicated for:
Improving periocular skin texture and tone
Reducing fine lines and early wrinkles
Enhancing hydration and elasticity of the eye contour
Rejuvenating tired, dull, or crepey under-eye skin
Treatment Areas:
Under-eye region (tear trough)
Lateral canthal area (crow’s feet)
Upper eyelid contour (if indicated and medically appropriate)
Clinical Benefits
Improves skin density and microcirculation
Enhances hydration, tone, and elasticity
Reduces fine wrinkles and fatigue signs
Promotes tissue regeneration through fibroblast stimulation
Safe and biocompatible for sensitive eye-area skin
Treatment Protocol
Frequency & Duration:
To be determined by a licensed practitioner according to patient needs.
Typical clinical use:
3–4 sessions at 15–21 day intervals
Maintenance every 3–6 months, depending on skin condition
Injection Depth: Intradermal
Technique: Microdroplet (0.1–0.2 ml per injection point) for uniform distribution and precise control
Aftercare Recommendations
Avoid direct sunlight and high temperatures for 24–48 hours
Refrain from rubbing or massaging the treated area
Use gentle skincare products suitable for the periocular region
Maintain hydration and avoid makeup for at least 12 hours post-treatment
Duration of Results
Visible rejuvenation and improved elasticity are typically observed after the first few sessions, with results lasting 6 to 9 months, depending on individual skin type, lifestyle, and treatment frequency.
Manufacturer & Regulatory Information
Manufacturer: Mastelli S.r.l. Officina Bio-Farmaceutica, Sanremo, Italy
Compliance:
• CE-marked Medical Device under EU Regulation (MDR) 2017/745
• ISO 13485 certified manufacturer
• Distributed under compliance with AEMPS (Agencia Española de Medicamentos y Productos Sanitarios) in Spain and the European Union
For Professional Use Only:
As trusted distributors and providers of aesthetic medicine, Aesthisave® emphasizes that our products are strictly for professional use.
We insist that these treatments be administered only by trained and medically qualified personnel, ensuring the highest standards of safety, precision, and patient care.
