MASTELLI PLINEST ONE 5x4 ml – Targeted Bioreparant for Skin Laxity and Stretch Marks
MASTELLI PLINEST ONE, developed by Mastelli S.r.l. Officina Bio-Farmaceutica (Italy), is a next-generation bioreparant formulated to improve skin firmness, elasticity, and the appearance of stretch marks in younger patients.
It harnesses the patented PN-HPT® (Polynucleotide High Purification Technology) to deliver regenerative benefits with exceptional purity and efficacy.
Product Overview
PLINEST ONE provides a scientifically advanced approach to skin repair and regeneration, stimulating fibroblast activity and improving extracellular matrix quality.
It is ideal for treating early skin laxity and striae distensae (stretch marks), promoting smoother, more resilient skin with visible rejuvenation effects.
Technology & Composition
Active Ingredient: PN-HPT® (Highly Purified Polynucleotides)
Concentration: 2 mg/ml
Mechanism: Cellular biorepair through fibroblast activation, increased hydration, and collagen remodeling
Key Features:
High purity guaranteed by PN-HPT® purification technology
Deep dermal biostimulation for elasticity and tissue regeneration
Excellent biocompatibility and tolerance profile
Packaging
5 sterile vials of 4 ml each
Product labels
Professional instructions for use
Indications & Treatment Areas
MASTELLI PLINEST ONE is indicated for:
Skin Laxity: Improves firmness and elasticity
Striae Distensae (Stretch Marks): Reduces appearance and improves texture
Treatment Areas:
Abdomen and thighs
Breasts and hips
Arms and buttocks
Areas with early signs of sagging or stretch marks
Clinical Benefits
Improves skin tone and texture
Enhances elasticity and firmness
Reduces visibility of stretch marks
Promotes dermal regeneration and collagen synthesis
Restores youthful skin structure
Treatment Protocol
Phase I (Initial):
Frequency: Every 7–14 days
Sessions: 4 sessions
Phase II (Maintenance):
Frequency: Every 21–30 days
Sessions: 4 additional sessions
Injection Depth: Intradermal, ensuring even and controlled product distribution for optimal results.
Aftercare Recommendations
Avoid sun exposure for at least 48 hours after treatment
Maintain optimal skin hydration
Avoid strong exfoliants, peels, or invasive procedures for 5–7 days
Duration of Results
Visible improvement is typically observed after the initial treatment phase, with cumulative effects lasting 6 to 9 months, depending on skin type and lifestyle.
Manufacturer & Regulatory Information
Manufacturer: Mastelli S.r.l. Officina Bio-Farmaceutica, Sanremo, Italy
Compliance:
• CE-marked Medical Device under EU Regulation (MDR) 2017/745
• ISO 13485 certified manufacturer
• Distributed under compliance with AEMPS (Agencia Española de Medicamentos y Productos Sanitarios) in Spain and the European Union
For Professional Use Only:
As trusted distributors and providers of aesthetic medicine, Aesthisave® emphasizes that our products are strictly for professional use.
We insist that these treatments be administered only by trained and medically qualified personnel, ensuring the highest standards of safety, precision, and patient care.
