CROMA PolyPhil Eye 1x2 ml – Advanced Polynucleotide Biostimulator for the Periocular Area
 
CROMA PolyPhil Eye 1x2 ml is an advanced injectable biostimulator specifically developed for the delicate periocular region.
Formulated with high-purity polynucleotides (PN-HPT™), it regenerates and revitalizes the under-eye area by improving tissue quality, boosting hydration, and enhancing skin elasticity.
Unlike traditional fillers, PolyPhil Eye does not add artificial volume. Instead, it works biologically, stimulating cellular renewal and microcirculation to reduce dark circles, fine lines, and fatigue for a brighter and more rested appearance.
 
Product Overview
PolyPhil Eye is part of Croma-Pharma’s regenerative biostimulatory line, designed to improve skin quality, tone, and density through natural cell activation.
It offers a gentle yet effective solution for patients concerned with periocular aging or dehydration, providing gradual, natural rejuvenation without swelling or heaviness.
 
Technology & Composition
Technology: PN-HPT™ (Polynucleotides Highly Purified Technology) — advanced purification ensuring safe, biocompatible polynucleotides for skin regeneration and hydration.
Composition:
• Polynucleotides (high purity) – promote fibroblast stimulation and dermal tissue repair.
• Buffer solution – maintains isotonic balance and physiological pH.
Packaging (Content):
• 1 sterile vial of 2 ml
• Instruction leaflet for professional use
• Single-patient use only
 
Indications & Treatment Areas
Dark circles and periorbital pigmentation
Fine lines and wrinkles around the eyes
Loss of firmness and elasticity in the under-eye zone
Tired or dehydrated skin requiring revitalization
 
Clinical Benefits
Stimulates fibroblast activity and tissue regeneration
Improves microcirculation and cellular oxygenation
Enhances hydration and dermal density
Reduces dark circles and eye fatigue
Non-volumizing: natural correction without puffiness or swelling
Improves luminosity and skin tone in the delicate eye area
 
Treatment Protocol
Initial course: 3–4 sessions, spaced 2–3 weeks apart
Maintenance: every 4–6 months depending on clinical assessment
Application: microinjections into the lower eyelid and periocular area using mesotherapy or micropapule technique
Duration of results: visible improvements from the second session, lasting 6–9 months depending on individual skin condition and lifestyle
 
Manufacturer & Regulatory Information
Manufactured by CROMA-Pharma GmbH (Austria).
CE-marked Class III Medical Device under EU Regulation (MDR) 2017/745.
ISO 13485 certified manufacturer.
Distributed under compliance with AEMPS (Agencia Española de Medicamentos y Productos Sanitarios) in Spain and the European Union.
 
For Professional Use Only:
As trusted distributors and providers of aesthetic medicine, Aesthisave® emphasizes that our products are strictly for professional use.
We insist that these treatments be administered only by trained and medically qualified personnel, ensuring the highest standards of safety and patient care.