ELLANSÉ™ M 2x1 ml – Collagen-Stimulating Dermal Filler for Long-Lasting Facial Rejuvenation
 
ELLANSÉ™ M 2x1 ml is a next-generation collagen-stimulating dermal filler developed by Sinclair Pharma (United Kingdom).
Formulated with polycaprolactone (PCL) microspheres suspended in a carboxymethylcellulose (CMC) gel carrier, it provides immediate volume restoration while triggering natural neocollagenesis for long-term skin rejuvenation.
Unlike conventional hyaluronic acid fillers, Ellansé™ M not only corrects wrinkles and folds but also enhances dermal quality, elasticity, and structure, with results lasting up to 24 months.
 
Product Overview
Ellansé™ M combines instant correction and progressive collagen regeneration in a single treatment.
It provides immediate lift and structure through its gel matrix while stimulating Type I collagen synthesis, offering both aesthetic enhancement and biological renewal.
The longevity of results is determined by the polycaprolactone chain length, which defines the gradual bioresorption rate — making Ellansé™ M the mid-term option (approx. 24 months) within the Ellansé range.
 
Technology & Composition
Technology: PCL-based collagen stimulator
Composition:
• 30% Polycaprolactone (PCL) microspheres (25–50 µm) – biocompatible and fully bioresorbable
• 70% Carboxymethylcellulose (CMC) gel carrier – provides immediate volume
Mode of Action: Dual-phase – immediate volumization from CMC and long-term collagen induction from PCL microspheres
Packaging (Content):
• 2 prefilled syringes x 1 ml each
• 4 sterile needles (27G ¾”)
• Product labels and professional instructions
 
Indications & Treatment Areas
ELLANSÉ™ M is indicated for the correction of moderate to deep wrinkles, facial folds, and volume loss, while stimulating collagen for long-term dermal rejuvenation.
 
Recommended Treatment Areas:
Cheeks and cheekbones
Nasolabial folds
Jawline definition
Chin augmentation
Not suitable for lips or periorbital zones.
 
Clinical Benefits
Immediate Volume & Lift: CMC carrier restores fullness instantly.
Collagen Biostimulation: PCL microspheres trigger sustained neocollagenesis (Type I collagen).
Long-Lasting Results: Effects typically last up to 24 months, twice the longevity of HA fillers.
Improves Skin Elasticity & Firmness: Progressive structural regeneration for smoother, more youthful skin.
Safe & Biocompatible: Fully bioresorbable with proven clinical safety record.
 
Treatment Protocol
Injection Depth: Deep dermis to subcutaneous layer
Technique: Linear retrotracing, fanning, or cross-hatching depending on indication
Recommended Schedule: Single treatment; maintenance session may be performed after 18–24 months
Procedure Time: Approximately 30 minutes
Post-Treatment Care: Avoid pressure, massage, or cosmetic procedures in treated areas for 48 hours
 
Duration of Results
Results are visible immediately and improve progressively as new collagen forms.
Visible Effects: Immediate volume correction
Collagen Remodeling: Gradual improvement over 3–6 months
Longevity: Typically up to 2 years, depending on individual metabolism and treatment area
 
Manufacturer & Regulatory Information
Manufactured by Sinclair Pharma Ltd. (United Kingdom)
CE-marked Class III Medical Device under EU Regulation (MDR) 2017/745
ISO 13485 certified manufacturer
Distributed under compliance with AEMPS (Agencia Española de Medicamentos y Productos Sanitarios) in Spain and the European Union
 
For Professional Use Only:
As trusted distributors and providers of aesthetic medicine, Aesthisave® emphasizes that our products are intended strictly for professional use.
We insist that these treatments be administered only by licensed medical and healthcare professionals, ensuring the highest standards of safety, precision, and patient care.