RADIESSE® 3ML – Advanced Dermal Filler for Volume Restoration and Collagen Stimulation
RADIESSE® 3ML is a high-capacity dermal filler developed for facial contouring, structural definition, and long-lasting volume restoration.
Formulated with Calcium Hydroxylapatite (CaHA) microspheres, it delivers both instant volumization and gradual biostimulation, encouraging natural collagen and elastin synthesis for a firmer, more youthful appearance.This version does not contain lidocaine, making it suitable for patients sensitive to anesthetics or for practitioners who prefer to customize anesthesia use.
Product Overview
RADIESSE® 3ML is ideal for treating larger facial areas such as the jawline, chin, cheeks, and midface zones, where structural support and lifting are needed.
Upon injection, the gel carrier provides immediate correction, while the CaHA microspheres create a scaffold for collagen regeneration, resulting in progressive and sustained rejuvenation.It offers a dual mechanism: instant volumizing and long-term dermal biostimulation.
Composition & Technology
Active Ingredient:
Calcium Hydroxylapatite (CaHA) Microspheres (25–45 µm) suspended in an aqueous gel carrier (70% water, 30% glycerin and sodium carboxymethylcellulose).
Mechanism of Action:
Immediate volume correction from the gel carrier.
Long-term stimulation of collagen (Types I and III) and elastin through CaHA integration.
Technology:
Patented CaHA microsphere suspension ensures controlled biodegradation and neocollagenesis.
Formulation Type:
Injectable implant for subdermal and supraperiosteal application.
Content
1 x 3 ml pre-filled syringe of RADIESSE® (without lidocaine)
Product labels
Professional use instructions
Indications
Facial volume restoration in cheeks, jawline, chin, and temples
Correction of deep wrinkles and folds
Structural support for facial contour enhancement
Treatment of midface laxity and tissue sagging
Bio-rejuvenation through collagen and elastin stimulation
Treatment Areas
Cheeks and midface
Jawline
Chin
Marionette lines
Nasolabial folds
Temples
Clinical Benefits
Instant lifting and contouring effect
Stimulates collagen and elastin for progressive rejuvenation
Restores facial harmony and definition
Improves skin texture, elasticity, and firmness
Long-lasting results — typically 12 to 18 months
Minimally invasive with little to no downtime
Treatment Protocol
Administration: Performed by trained medical professionals using a needle or cannula, depending on the anatomical area.
Procedure: The area is cleaned and may be pre-treated with topical anesthetic. RADIESSE® is injected into the deep dermis or subdermal plane.
Post-Treatment: Minor swelling, redness, or tenderness may occur and typically resolves within 24–48 hours.
Maintenance: Touch-up sessions can be scheduled as needed to maintain optimal volume and definition.
Manufacturer & Regulatory Information
Manufacturer: Merz Aesthetics GmbH (Germany)
Compliance:
• CE-marked Class III Medical Device under EU Regulation (MDR) 2017/745
• ISO 13485 certified manufacturer
• Distributed under compliance with AEMPS (Agencia Española de Medicamentos y Productos Sanitarios) in Spain and the European Union
For Professional Use Only:
As trusted distributors and providers of aesthetic medicine, Aesthisave® emphasizes that our products are strictly for professional use.
We insist that these treatments be administered only by trained and medically qualified personnel, ensuring the highest standards of safety, precision, and patient care.
