RADIESSE® 1.5ML LIDOCAINE – Advanced Collagen Stimulating Filler for Volume and Contouring
RADIESSE® 1.5ML LIDOCAINE is an advanced injectable dermal filler designed for facial volume restoration, contouring, and wrinkle correction.
Formulated with Calcium Hydroxylapatite (CaHA) microspheres suspended in a biodegradable gel carrier and enriched with lidocaine, it provides instant results and long-term collagen stimulation with enhanced patient comfort.This treatment delivers both immediate lifting and lasting skin regeneration, ideal for addressing deep wrinkles, facial asymmetry, and loss of definition in key facial areas.
Product Overview
RADIESSE® with Lidocaine offers a dual-action mechanism:
Instant correction through immediate volumization.
Biostimulation by activating fibroblasts to produce new collagen and elastin fibers over time.
Its CaHA microspheres form a supportive scaffold beneath the skin, gradually replaced by newly generated tissue, achieving natural and long-lasting rejuvenation.
The addition of 0.3% lidocaine ensures a smoother, more comfortable injection experience.
Composition & Technology
Active Ingredients:
Calcium Hydroxylapatite (CaHA) microspheres (25–45 µm) suspended in an aqueous gel carrier (70% water, 30% glycerin and sodium carboxymethylcellulose).
Lidocaine Hydrochloride 0.3% (3 mg/ml) for local anesthesia and pain reduction.
Mechanism of Action:
Immediate volumizing through the gel carrier.
Gradual neocollagenesis as CaHA microspheres stimulate fibroblasts.
Technology:
Patented CaHA microsphere suspension for controlled degradation and collagen stimulation.
Formulation Type:
Injectable implant for deep dermal or subdermal application.
Content
1 x 1.5 ml pre-filled syringe of RADIESSE® with Lidocaine
Product labels
Professional use instructions
Indications
Moderate to deep wrinkle correction (nasolabial folds, marionette lines, and chin wrinkles)
Facial contouring of the jawline, chin, and midface
Restoration of lost volume in cheeks and temples
Non-surgical nose reshaping and profile correction
Rejuvenation of the hands for improved tone and firmness
Treatment Areas
Nasolabial folds
Marionette lines
Cheeks
Chin and jawline
Nose (non-surgical correction)
Hands
Clinical Benefits
Instant lifting and volumizing effect
Stimulates collagen and elastin production for long-term firmness
Improves skin elasticity, tone, and structure
Provides natural-looking, harmonious results
Minimizes discomfort thanks to integrated lidocaine
Durable results lasting 12–18 months depending on individual factors
Treatment Protocol
Administration: Performed by licensed professionals using needle or cannula.
Preparation: The area is cleansed and may be pre-numbed with anesthetic cream.
Injection Depth: Deep dermis or subdermal plane for volume and contouring.
Post-Treatment: Mild swelling or redness may occur and typically resolves within 24–48 hours.
Maintenance: Touch-ups may be recommended to maintain optimal results.
Manufacturer & Regulatory Information
Manufacturer: Merz Aesthetics GmbH (Germany)
Compliance:
• CE-marked Class III Medical Device under EU Regulation (MDR) 2017/745
• ISO 13485 certified manufacturer
• Distributed under compliance with AEMPS (Agencia Española de Medicamentos y Productos Sanitarios) in Spain and the European Union
For Professional Use Only:
As trusted distributors and providers of aesthetic medicine, Aesthisave® emphasizes that our products are strictly for professional use.
We insist that these treatments be administered only by trained and medically qualified personnel, ensuring the highest standards of safety, precision, and patient care.
















