CROMA Saypha® Volume 1x1 ml – Cross-Linked Hyaluronic Acid Filler for Deep Facial Volume Restoration
 
CROMA Saypha® Volume 1x1 ml is a highly elastic cross-linked hyaluronic acid dermal filler developed by CROMA-Pharma GmbH (Austria).
It is designed to restore facial volume, enhance contours, and correct deep wrinkles and folds, offering natural-looking, long-lasting rejuvenation.
The advanced cross-linking technology ensures excellent volumizing capacity and smooth integration into the skin, achieving a refreshed, youthful, and balanced appearance.
 
Product Overview
Part of the Saypha® professional range, this filler is formulated for deep dermal and subcutaneous injection, ideal for restoring lost facial structure and definition in areas affected by aging or significant volume depletion.
 
Technology & Composition
Technology: Patented S.M.A.R.T. cross-linking process (Supreme Monophasic and Reticulated Technology) – ensures high elasticity, homogeneous gel consistency, and natural results.
Composition:
• Cross-linked Hyaluronic Acid (23 mg/ml) – provides durable structure and volume.
• Phosphate buffer (pH 7.1) – maintains stability and comfort during injection.
• No lidocaine.
Packaging (Content):
• 1 prefilled sterile syringe of 1 ml
• 2 sterile 27G ½” needles
• Instruction leaflet and traceability labels
• For single-patient use only
 
Indications & Treatment Areas
Saypha® Volume is indicated for the correction of deep wrinkles, folds, and areas with pronounced volume loss.
 
Recommended Treatment Areas:
Cheeks (volumization and contouring)
Nasolabial folds
Marionette lines
Chin and jawline definition
Temples
 
Clinical Benefits
Restores deep facial volume with long-lasting natural results
Rebuilds structure and contour in areas affected by aging
Smooths deep wrinkles and folds
Provides immediate lifting and firming effect
High viscosity and elasticity for optimal tissue integration
 
Treatment Protocol
Application: Deep dermis to subcutaneous layer using linear, fanning, or cross-hatching techniques.
Sessions: Single session with optional touch-up after 2–4 weeks if necessary.
Duration of results: typically 12–18 months, depending on treatment area, skin type, and injection technique.
 
Manufacturer & Regulatory Information
Manufactured by CROMA-Pharma GmbH (Austria).
CE-marked Class III Medical Device under EU Regulation (MDR) 2017/745.
ISO 13485 certified manufacturer.
Distributed under compliance with AEMPS (Agencia Española de Medicamentos y Productos Sanitarios) in Spain and the European Union.
 
For Professional Use Only:
As trusted distributors and providers of aesthetic medicine, Aesthisave® emphasizes that our products are strictly for professional use.
We insist that these treatments be administered only by trained and medically qualified personnel, ensuring the highest standards of safety and patient care.