CROMA PhilArt Injectable Polynucleotides 1x2 ml – Advanced Biostimulator for Skin Regeneration and Collagen Activation
 
CROMA PhilArt Injectable Polynucleotides 1x2 ml is a regenerative injectable treatment developed by CROMA-Pharma GmbH (Austria).
Formulated with high-purity PN-HPT™ polynucleotides, it works to revitalize, hydrate, and strengthen the skin by stimulating collagen and elastin synthesis and enhancing tissue repair.
This non-volumizing biostimulator improves skin texture, tone, and elasticity, delivering gradual, natural-looking rejuvenation for patients seeking refined, healthy, and radiant skin.
 
Product Overview
PhilArt Injectable Polynucleotides (also known as PhilArt Face) is part of Croma’s PhilArt line of polynucleotide-based biostimulators.
It is designed for the face and neck, providing visible improvement in skin density, hydration, and firmness while supporting dermal regeneration from within.
 
Technology & Composition
Technology: PN-HPT™ (Polynucleotides Highly Purified Technology) – long-chain, ultra-pure DNA fragments with regenerative and antioxidant activity.
Composition:
• Polynucleotides (high purity) – stimulate fibroblast activity, promoting collagen and elastin synthesis.
• Buffer solution – ensures physiological pH and osmotic balance.
• No hyaluronic acid or cross-linking agents.
Packaging (Content):
• 1 sterile prefilled vial of 2 ml
• Product labeling and professional instructions
• For single-patient use only
 
Indications & Treatment Areas
Facial rejuvenation and dermal revitalization
Fine lines and loss of firmness
Dull, dehydrated, or tired-looking skin
Post-procedure regeneration (PRP, mesotherapy, microneedling)
 
Recommended Treatment Areas:
Face, neck, décolleté, and hands.
 
Clinical Benefits
Stimulates natural collagen and elastin production
Improves elasticity, hydration, and skin tone
Reduces fine lines and signs of fatigue
Supports dermal healing and antioxidant protection
Non-volumizing and biocompatible, ideal for subtle and natural rejuvenation
 
Treatment Protocol
Sessions: 3–4 sessions spaced 2–3 weeks apart
Maintenance: every 6–9 months depending on skin condition
Application: superficial to mid-dermal microinjections using mesotherapy technique
Duration of results: visible after the first sessions, lasting 6–12 months depending on patient age and skin quality
 
Manufacturer & Regulatory Information
Manufactured by CROMA-Pharma GmbH (Austria).
CE-marked Class III Medical Device under EU Regulation (MDR) 2017/745.
ISO 13485 certified manufacturer.
Distributed under compliance with AEMPS (Agencia Española de Medicamentos y Productos Sanitarios) in Spain and the European Union.
 
For Professional Use Only:
As trusted distributors and providers of aesthetic medicine, Aesthisave® emphasizes that our products are strictly for professional use.
We insist that these treatments be administered only by trained and medically qualified personnel, ensuring the highest standards of safety and patient care.