DISOLVIDASE HYALURONIDASE 1.500 I.U – Professional Enzymatic Solution for Hyaluronic Acid Dissolution
 
DISOLVIDASE HYALURONIDASE 1.500 I.U is a sterile, lyophilized enzyme preparation specifically designed to degrade and remove hyaluronic acid-based dermal fillers.
Formulated for professional aesthetic use, it enables safe correction of overfilling, asymmetry, nodules, or vascular complications following HA filler procedures.
This high-purity hyaluronidase effectively hydrolyzes hyaluronic acid molecules, restoring the treated area to its natural state and supporting optimal aesthetic outcomes.
 
Product Overview
DISOLVIDASE acts by catalyzing the depolymerization of hyaluronic acid, reducing its viscosity and promoting resorption.
It provides a controlled and reliable solution for professionals managing overcorrection, uneven filler placement, or emergency reversal of HA filler complications.
This product ensures predictable, safe, and efficient enzyme activity with minimal tissue irritation.
 
Technology & Composition
Formulation Type: Lyophilized powder for reconstitution
Active Ingredient: Hyaluronidase 1.500 I.U. (enzymatic activity)
Excipients: Mannitol (stabilizing agent)
Form: Sterile, freeze-dried powder in glass vial
Packaging (Content):
• 5 vials x 1.500 I.U. each
• Sterile and sealed under aseptic manufacturing conditions
 
Indications & Treatment Areas
DISOLVIDASE HYALURONIDASE is indicated for:
Dissolution of unwanted hyaluronic acid dermal fillers
Correction of overfilling or irregularities after filler injection
Management of nodules or lumps caused by HA-based fillers
Treatment of vascular compromise (ischemia) caused by inadvertent HA intravascular injection (emergency use under medical supervision)
 
Applicable Treatment Areas:
Face (lips, cheeks, nasolabial folds, chin, jawline)
Body areas previously treated with HA fillers
 
Clinical Benefits
Precise and effective degradation of hyaluronic acid fillers
Quick action within minutes to hours after injection
Improved patient safety in correction and emergency management
Supports optimal aesthetic correction with controlled enzyme diffusion
Sterile and pharmaceutical-grade formulation ensuring professional reliability
 
Treatment Protocol
Reconstitution: Dissolve one vial (1500 I.U.) in 1–2 ml of sterile saline (0.9% NaCl) before use.
Administration Route: Intradermal or subcutaneous injection, depending on filler location.
Dosage: Adjust according to the amount and density of filler being dissolved.
Procedure Time: Typically 15–30 minutes, with effects visible within hours.
Post-treatment: Avoid re-injection of HA fillers for at least 1–2 weeks post-procedure.
 
Duration of Action
The enzyme activity begins within minutes and continues over several hours, leading to progressive degradation of HA filler material.
Results are typically visible immediately to within 24 hours post-treatment.
 
Manufacturer & Regulatory Information
Manufactured by DERMAQUAL PARIS (FRANCE)
CE-marked Class III Medical Device under EU Regulation (MDR) 2017/745
ISO 13485 certified manufacturer
Distributed under compliance with AEMPS (Agencia Española de Medicamentos y Productos Sanitarios) in Spain and the European Union
 
For Professional Use Only:
As trusted distributors and providers of aesthetic medicine, Aesthisave® emphasizes that our products are intended strictly for professional use.
We insist that these treatments be administered only by licensed medical and healthcare professionals trained in injection techniques, ensuring safety, accuracy, and patient care excellence.